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Unraveling the Genetic Basis of HIV Control

Unraveling the Genetic Basis of HIV Control
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This video is available at the Physicians Research Network website.

Original Release Date: 11/16/2010
Review Date: 11/16/2010
  • Bruce Walker, MD
    Director, Professor of Medicine
    Ragon Institute of MGH, MIT and Harvard Medical School
Learning Objectives / Desired Outcomes
At the completion of this educational activity, participants will:
  1. Better appreciate the use of genome-wide association scans to understand human disease.
  2. Describe the genetic basis for control and lack of control of HIV.
  3. Discuss the implications of genetic studies for vaccine design.
  4. Understand the effects of immune selection pressure on viral fitness.
Presenter Bio
Bruce Walker, MD
Bruce Walker is the Director of the Ragon Institute of MGH, MIT and Harvard, a Professor of Medicine at Harvard Medical School, a Professor of Practice at MIT and a Howard Hughes Medical Institute Investigator. In addition to his clinical duties as a board certified Infectious Disease specialist, his research focuses on cellular immune responses in chronic viral infections, with a particular focus on HIV. He leads an international translational clinical and basic science research effort to understand how some rare people who are infected with HIV, but have never been treated, can fight the virus with their immune system. Dr. Walker is also an Adjunct Professor at the Nelson Mandela School of Medicine in Durban, South Africa. There he collaborates with the Doris Duke Medical Research Institute at the University of KwaZulu-Natal and serves as a Principal Investigator in the HIV Pathogenesis Program, an initiative to study the evolution of the HIV and the immune responses effective in controlling this virus, as well as to contribute to training African scientists.
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